SANDELIN LAB
medical transcriptomics and computational biology
The Sandelin group is both computational and experimental, focused on fundamental gene regulation and medical genomics. In particular, we specialise in tag-based sequencing analysis to find alternative promoters and enhancers, and gene regulation bioinformatics. Highlights include our atlases of promoters and enhancers across the human body, our work on inflammatory diseases and the widely used JASPAR database.
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R E S O U R C E S
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JASPAR - High quality transcription factor binding site motifs. A standard resource in bioinformatics with >800 citations
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SpliceR - a tool to analyze RNA-seq alternative splice events in R.
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Enhancer/promoter selector - A slider-based interface to selecting tissue/cell-restricted enhancers or promoters from the FANTOM set
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NHR-scan - a HMM-based prediction of nuclear receptor binding sites