Principles for RNA metabolism and alternative transcription initiation within closely spaced promote
Our latest article by Yun Chen et al - published in Nature genetics at http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3616.html...
LAMC2 is regulated by the master regulator CDX2
Mehmet Coskun et al published a report in J Cell Biochem showing that the LAMC2 gene is regulated by the master regulator CDX2 in...
Grant from the Danish Council for Independent Research
We received a grant from the Danish Council for Independent Research to investigate differences between inflammatory bowel disease...
Regulating retrotransposon activity through the use of alternative transcription start sites.
Retrotransposons, the ancestors of retroviruses, have the potential for gene disruption and genomic takeover if not kept in check....
New Pan-Cancer Biomarkers through CAGE analysis.
Genes that are commonly deregulated in cancer are clinically attractive as candidate pan-diagnostic markers and therapeutic targets. To...
JASPAR 2016 - a new generation of the popular database
JASPAR (http://jaspar.genereg.net) is an open-access database storing curated, non-redundant transcription factor (TF) binding profiles...
Remodeling of retrotransposon elements during epigenetic induction of adult visual cortical plastici
The capacity for plasticity in the adult brain is limited by the anatomical traces laid down during early postnatal life. Removing...
Comment on the near-universal bidirectional transcription of human promoters in Molecular Cell
We have published a commentary on a recent paper by Duttke et al, who suggested that are “human promoters are intrinsically...
Death and birth or promoters
We contributed to a paper in Genome Research on promoter evolution, using mathed tissue samples from human and mouse. A highlight is...
Enhancers and promoters - two sides of the same coin?
New oppinion piece in Trends in Genetics together with Robin Andersson and Charles Danko exploring the differences and similarities...